Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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541
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555
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541
Tocris Bioscience™ VH 032 amide-alkylC2-acid
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VHL ligand with alkyl linker and terminal acid for onward chemistry
542
Tocris Bioscience™ Repaglinide
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CAS: 135062-02-1 Molecular Formula: C27H36N2O4
| CAS | 135062-02-1 |
|---|---|
| Molecular Formula | C27H36N2O4 |
543
Tocris Bioscience™ SB 772077B dihydrochloride
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CAS: 607373-46-6 Molecular Formula: C15H20Cl2N8O2
| CAS | 607373-46-6 |
|---|---|
| Molecular Formula | C15H20Cl2N8O2 |
544
Tocris Bioscience™ PROTAC™(H-PGDS)-8
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for PROTAC™(H-PGDS)-7 (Cat. No. 8004)
545
Tocris Bioscience™ Valsartan
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity, selective AT1 antagonist
| Inhibitors | Valsartan |
|---|---|
| Product Type | Valsartan |
| Molecular Weight (g/mol) | 435.52 |
| Purity | >99% |
546
Tocris Bioscience™ Sodium Cromoglicate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
547
Tocris Bioscience™ DQP 1105
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 380560-89-4 Molecular Formula: C29H24BrN3O4
| CAS | 380560-89-4 |
|---|---|
| Molecular Formula | C29H24BrN3O4 |
548
Tocris Bioscience™ SCH 50911
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 733717-87-8 Molecular Formula: C8H15NO3
| CAS | 733717-87-8 |
|---|---|
| Molecular Formula | C8H15NO3 |
549
Tocris Bioscience™ Gilteritinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent FLT3 inhibitor; also potently inhibits AXL
| Target | Flt-3/Flk-2/CD135 |
|---|---|
| CAS | 1254053-43-4 |
| Purity | 0.98 |
| Chemical Name or Material | 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H44N8O3 |
550
Tocris Bioscience™ VU 0364739 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1244640-48-9 Molecular Formula: C26H28ClFN4O2
| CAS | 1244640-48-9 |
|---|---|
| Molecular Formula | C26H28ClFN4O2 |
551
Tocris Bioscience™ RA 839
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Nrf2 activator; inhibits Nrf2/Keap1 interaction
| Target | Nrf2 Modulators |
|---|---|
| CAS | 1832713-02-6 |
| Purity | >98% |
| Chemical Name or Material | (3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C25H28N2O4S |
| Formula Weight | 452.57 |
552
| Shipping Condition | No special requirements |
|---|---|
| CAS | 118876-58-7 |
| Color | Almost-white to Yellow |
| Purity | ≥98% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | NBQX |
| Recommended Storage | Refrigerator +4°C |
| Synonym | 2,3-Dihydroxy-6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione; 6-Nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione |
| Molecular Formula | C12 H8 N4 O6 S |
| Product Line | Life science |
553
Tocris Bioscience™ RU.521
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)
| Target | Synthase/Synthetase Inhibitors |
|---|---|
| CAS | 2262452-06-0 |
| Purity | 0.98 |
| Chemical Name or Material | 3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H12Cl2N4O3 |
554
555
Tocris Bioscience™ PD 102807
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 23062-91-1 Molecular Formula: C23H24N2O4
| CAS | 23062-91-1 |
|---|---|
| Molecular Formula | C23H24N2O4 |